Best Practice & Research Clinical Obstetrics & Gynaecology
Volume 25, Issue 6 , Pages 705-718 , December 2011

Pathology of mixed Müllerian tumours

References 

  1. McCluggage WG, Haller U, Kurman RJ, et al. Mixed epithelial and mesenchymal tumours. In:  Tavassoli FA,  Devilee P editor. World Health Organization classification of tumours. Pathology and genetics of tumours of the breast and female genital organs. Lyon: IARC Press; 2003;p. 245–249
  2. Zaloudek CJ, Norris HJ. Adenofibroma and adenosarcoma of the uterus: a clinicopathologic study of 35 cases. Cancer. 1981;48:354–366
  3. Gallardo A, Prat J. Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. Am J Surg Pathol. 2009;33:278–288
  4. Horie Y, Ikawa S, Kadowaki K, et al. Lipoadenofibroma of the uterine corpus: report of a new variant of adenofibroma (benign Müllerian mixed tumor). Arch Pathol Lab Med. 1995;119:274–276
  5. Sinkre P, Miller DS, Milchgrub S, et al. Adenomyofibroma of the endometrium with skeletal muscle differentiation. Int J Gynecol Pathol. 2000;19:280–283
  6. Clement PB, Scully RE. Mullerian adenofibroma of the uterus with invasion of myometrium and pelvic veins. Int J Gynecol Pathol. 1990;9:363–371
  7. Clement PB, Scully RE. Mullerian adenosarcoma of the uterus: a clinicopathologic analysis of 100 cases with a review of the literature. Hum Pathol. 1990;21:363–381
  8. Clement PB, Scully RE. Mullerian adenosarcoma of the uterus. A clinicopathologic analysis of ten cases of a distinctive type of mullerian mixed tumor. Cancer. 1974;34:1138–1149
  9. Blom R, Guerrieri C. Adenosarcoma of the uterus: a clinicopathologic, DNA flow cytometric, p53 and mdm-2 analysis of 11 cases. Int J Gynecol Cancer. 1999;9:37–43
  10. Kaku T, Silverberg SG, Major FJ, et al. Adenosarcoma of the uterus: a Gynecologic Oncology Group clinicopathologic study of 31 cases. Int J Gynecol Pathol. 1992;11:75–88
  11. Clement PB, Scully RE. Extrauterine mesodermal (Mullerian) adenosarcoma: a clinicopathologic analysis of five cases. Am J Clin Pathol. 1978;69:276–283
  12. Eichhorn JH, Young RH, Clement PB, et al. Mesodermal (Mullerian) adenosarcoma of the ovary: a clinicopathologic analysis of 40 cases and a review of the literature. Am J Surg Pathol. 2002;26:1243–1258
  13. Inoue M, Fukuda H, Tanizawa O. Adenosarcomas originating from sites other than uterine endometrium. Int J Gynaecol Obstet. 1995;48:299–306
  14. Jones MW, Lefkowitz M. Adenosarcoma of the uterine cervix: a clinicopathological study of 12 cases. Int J Gynecol Pathol. 1995;14:223–229
  15. Arenas M, Rovirosa A, Hernández V, et al. Uterine sarcomas in breast cancer patients treated with tamoxifen. Int J Gynecol Cancer. 2006;16:861–865
  16. Clement PB, Oliva E, Young RH. Mullerian adenosarcoma of the uterine corpus associated with tamoxifen therapy: a report of six cases and a review of tamoxifen-associated endometrial lesions. Int J Gynecol Pathol. 1996;15:222–229
  17. Kerner H, Lichtig C. Mullerian adenosarcoma presenting as cervical polyps: a report of seven cases and review of the literature. Obstet Gynecol. 1993;81:655–659
  18. Manoharan M, Azmi MA, Soosay G, et al. Mullerian adenosarcoma of uterine cervix: report of three cases and review of literature. Gynecol Oncol. 2007;105:256–260
  19. Gollard R, Kosty M, Bordin G, et al. Two unusual presentations of mullerian adenosarcoma: case reports, literature review, and treatment considerations. Gynecol Oncol. 1995;59:412–422
  20. Oda Y, Nakanishi I, Tateiwa T. Intramural mullerian adenosarcoma of the uterus with adenomyosis. Arch Pathol Lab Med. 1984;108:798–801
  21. Soslow RA, Ali A, Oliva E. Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases. Am J Surg Pathol. 2008;32:1013–1021
  22. Fehmian C, Jones J, Kress Y, et al. Adenosarcoma of the uterus with extensive smooth muscle differentiation: ultrastructural study and review of the literature. Ultrastruct Pathol. 1997;21:73–79
  23. Lack EE, Bitterman P, Sundeen JT. Mullerian adenosarcoma of the uterus with pure angiosarcoma: case report. Hum Pathol. 1991;22:1289–1291
  24. Clement PB. Mullerian adenosarcomas of the uterus with sarcomatous overgrowth. A clinicopathological analysis of 10 cases. Am J Surg Pathol. 1989;13:28–38
  25. Amant F, Schurmans K, Steenkiste E, et al. Immunohistochemical determination of estrogen and progesterone receptor positivity in uterine adenosarcoma. Gynecol Oncol. 2004;93:680–685
  26. Amant F, Steenkiste E, Schurmans K, et al. Immunohistochemical expression of CD10 antigen in uterine adenosarcoma. Int J Gynecol Cancer. 2004;14:1118–1121
  27. Abeler VM, Royne O, Thoresen S, et al. Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients. Histopathology. 2009;54:355–364
  28. Seidman JD, Wasserman CS, Aye LM, et al. Cluster of uterine mullerian adenosarcoma in the Washington, DC metropolitan area with high incidence of sarcomatous overgrowth. Am J Surg Pathol. 1999;23:809–814
  29. McCluggage WG. Uterine carcinosarcomas (malignant mixed Mullerian tumors) are metaplastic carcinomas. Int J Gynecol Cancer. 2002;12:687–690
  30. Ferguson SE, Tornos C, Hummer A, et al. Prognostic features of surgical stage I uterine carcinosarcoma. Am J Surg Pathol. 2007;31:1653–1661
  31. Silverberg SG, Major FJ, Blessing JA, et al. Carcinosarcoma (malignant mixed mesodermal tumor) of the uterus. A Gynecologic Oncology Group pathologic study of 203 cases. Int J Gynecol Pathol. 1990;9:1–19
  32. Yamada SD, Burger RA, Brewster WR, et al. Pathologic variables and adjuvant therapy as predictors of recurrence and survival for patients with surgically evaluated carcinosarcoma of the uterus. Cancer. 2000;88:2782–2786
  33. Soslow RA, Bissonnette JP, Wilton A, et al. Clinicopathologic analysis of 187 high-grade endometrial carcinomas of different histologic subtypes: similar outcomes belie distinctive biologic differences. Am J Surg Pathol. 2007;31:979–987
  34. McCluggage WG. Malignant biphasic uterine tumours: carcinosarcomas or metaplastic carcinomas?. J Clin Pathol. 2002;55:321–325
  35. Bitterman P, Chun B, Kurman RJ. The significance of epithelial differentiation in mixed mesodermal tumors of the uterus. A clinicopathologic and immunohistochemical study. Am J Surg Pathol. 1990;14:317–328
  36. Geisinger KR, Dabbs DJ, Marshall RB. Malignant mixed mullerian tumors. An ultrastructural and immunohistochemical analysis with histogenetic considerations. Cancer. 1987;59:1781–1790
  37. Wada H, Enomoto T, Fujita M, et al. Molecular evidence that most but not all carcinosarcomas of the uterus are combination tumors. Cancer Res. 1997;57:5379–5385
  38. Castilla MA, Moreno-Bueno G, Romero-Pérez L, et al. Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma. J Pathol. 2011;223:72–80
  39. Zeisberg M, Neilson EG. Biomarkers for epithelial–mesenchymal transitions. J Clin Invest. 2009;119:1429–1437
  40. Flynt AS, Li N, Thatcher EJ, et al. Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate. Nat Genet. 2007;39:259–263
  41. Murray SK, Clement PB, Young RH. Endometrioid carcinomas of the uterine corpus with sex cord-like formations, hyalinization, and other unusual morphologic features: a report of 31 cases of a neoplasm that may be confused with carcinosarcoma and other uterine neoplasms. Am J Surg Pathol. 2005;29:157–166
  42. Silva EG, Deavers MT, Bodurka DC, et al. Association of low-grade endometrioid carcinoma of the uterus and ovary with undifferentiated carcinoma: a new type of dedifferentiated carcinoma?. Int J Gynecol Pathol. 2006;25:52–58
  43. Altrabulsi B, Malpica A, Deavers MT, et al. Undifferentiated carcinoma of the endometrium. Am J Surg Pathol. 2005;29:1316–1321
  44. Garg K, Leitao MM, Kauff ND, et al. Selection of endometrial carcinomas for DNA mismatch repair protein immunohistochemistry using patient age and tumor morphology enhances detection of mismatch repair abnormalities. Am J Surg Pathol. 2009;33:925–933
  45. George E, Lillemoe TJ, Twiggs LB, et al. Malignant mixed mullerian tumor versus high-grade endometrial carcinoma and aggressive variants of endometrial carcinoma: a comparative analysis of survival. Int J Gynecol Pathol. 1995;14:39–44
  46. Callister M, Ramondetta LM, Jhingran A, et al. Malignant mixed Müllerian tumors of the uterus: analysis of patterns of failure, prognostic factors, and treatment outcome. Int J Radiat Oncol Biol Phys. 2004;58:786–796
  47. Livi L, Paiar F, Shah N, et al. Uterine sarcoma: twenty-seven years of experience. Int J Radiat Oncol Biol Phys. 2003;57:1366–1373
  48. Villena-Heinsen C, Diesing D, Fischer D, et al. Carcinosarcomas-a retrospective analysis of 21 patients. Anticancer Res. 2006;26:4817–4823
  49. Mazur MT. Atypical polypoid adenomyomas of the endometrium. Am J Surg Pathol. 1981;5:473–482
  50. Young RH, Treger T, Scully RE. Atypical polypoid adenomyoma of the uterus. A report of 27 cases. Am J Clin Pathol. 1986;86:139–145
  51. Fukunaga M, Endo Y, Ushigome S, et al. Atypical polypoid adenomyomas of the uterus. Histopathology. 1995;27:35–42
  52. Clement PB, Young RH. Atypical polypoid adenomyoma of the uterus associated with Turner’s syndrome. Int J Gynecol Pathol. 1987;6:104–113
  53. Ota S, Catasus L, Matias-Guiu X, et al. Molecular pathology of atypical polypoid adenomyoma of the uterus. Hum Pathol. 2003;34:784–788
  54. Ohishi Y, Kaku T, Kobayashi H, et al. CD10 immunostaining distinguishes atypical polypoid adenomyofibroma (atypical polypoid adenomyoma) from endometrial carcinoma invading the myometrium. Hum Pathol. 2008;39:1446–1453
  55. Gilks CB, Clement PB, Hart WR, et al. Uterine adenomyomas excluding atypical polypoid adenomyomas and adenomyomas of endocervical type: a clinicopathologic study of 30 cases of an underemphasized lesion that may cause diagnostic problems with brief consideration of adenomyomas of other female genital tract sites. Int J Gynecol Pathol. 2000;19:195–205
  56. Tahlan A, Nanda A, Mohan H. Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature. Int J Gynecol Pathol. 2006;25:361–365
  57. Heatley MK. Atypical polypoid adenomyoma: a systematic review of the English literature. Histopathology. 2006;48:609–610

PII: S1521-6934(11)00100-3

doi: 10.1016/j.bpobgyn.2011.05.010

Best Practice & Research Clinical Obstetrics & Gynaecology
Volume 25, Issue 6 , Pages 705-718 , December 2011

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