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Volume 24, Issue 3, Pages 353-365 (June 2010)


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Challenges of major obstetric haemorrhage

Arlene Wise, FRCA (Consultant Obstetric Anaesthetist)aemail address, Vicki Clark, FRCA (Consultant Obstetric Anaesthetist)Corresponding Author Informationbemail address

published online 11 January 2010.

Every minute of every day, a woman dies in pregnancy or childbirth. The biggest killer is obstetric haemorrhage, the successful treatment of which is a challenge for both the developed and developing worlds. The presence of an attendant at every birth and access to emergency obstetric care are key to reducing maternal morbidity and mortality in the developing world while resource-rich countries have a rising caesarean section rate with its consequential effect on the incidence of abnormal placentation and its link with peripartum hysterectomy.

Management of obstetric haemorrhage involves early recognition, assessment and resuscitation. Various methods are available to try to stop the bleeding – from pharmacological methods to aid uterine contraction (e.g., oxytocinon, ergometrine and prostaglandins) to surgical methods to stem the bleeding (e.g., balloon tamponade, compression sutures or arterial ligation). Interventional radiology can be used if placenta accreta is suspected. Cell salvage has been introduced into obstetrics relatively recently in an attempt to reduce allogeneic transfusion.

Simpson Centre for Reproductive Health, Royal Infirmary, 51 Little France Crescent, Edinburgh, EH16 4SA, UK

Corresponding Author InformationCorresponding author. Tel.: +44 131 536 1000; Fax: +44 1312423174.

a Her interests include high-dependency care in obstetrics and training in skills and drills. Tel.: +44 131 536 1000.

b She has served on the committee of the Obstetric Anaesthetists' Association and her interests include regional anaesthesia, fibre-optic intubation, teaching and audit.

PII: S1521-6934(09)00150-3

doi:10.1016/j.bpobgyn.2009.11.011


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