Best Practice & Research Clinical Obstetrics & Gynaecology
Volume 16, Issue 4 , Pages 499-512 , August 2002

Pathology of borderline (low malignant potential) ovarian tumours

  • Jeffrey D Seidman, MD (Director of Gynecological Pathology)

      Affiliations

    • Department of Pathology, Washington Hospital Center, Washington, DC, USA
    • ,
  • Brigitte M Ronnett, MD (Associate Professor of Pathology, The Johns Hopkins, University School of Medicine and Pathologist, The Johns Hopkins Hospital, Baltimore, MD)

      Affiliations

    • Departments of Pathology and Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • ,
  • Robert J Kurman, MD (Richard W. Te Linde Distinguished Professor of Gynecologic Pathology, Departments of Gynecology, Obstetrics and Pathology)

      Affiliations

    • Departments of Pathology and Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

References 

    REFERENCES
  1. Serov SF, Scully RE, Sobin LH. Histologic typing of ovarian tumours. International Histological Classification and Staging of Tumours. Geneva: World Health Organization; 1973;
  2. Acta Obstetricia et Gynecologica Scandinavica. 1971;50:1–7
  3. Seidman JD, Kurman RJ. Ovarian serous borderline tumours: a critical review of the literature with emphasis on prognostic indicators. Human Pathology. 2000;31:539–557
  4. Kurman RJ, Trimble CL. The behaviour of serous tumours of low malignant potential: are they ever malignant?. International Journal of Gynecological Pathology. 1993;12:120–127
  5. Bell DA, Weinstock MA, Scully RE. Peritoneal implants of ovarian serous borderline tumours: histologic features and prognosis. Cancer. 1988;62:2212–2222
  6. Russell P, Merkur H. Proliferating ovarian ‘epithelial’ tumours: a clinicopathological analysis of 144 cases. Australia and New Zealand Journal of Obstetrics and Gynaecology. 1979;19:45–51
  7. Seidman JD, Kurman RJ. Subclassification of serous borderline tumours of the ovary into benign and malignant types: a clinicopathologic study of 65 advanced stage cases. American Journal of Surgical Pathology. 1996;20:1331–1345
  8. Gershenson DM. Contemporary treatment of borderline ovarian tumours. Cancer Investigation. 1999;17:206–210
  9. Bell KA, Sedhev A ES, Kurman RJ. Refined diagnostic criteria for implants associated with ovarian atypical proliferative serous tumours (borderline) and micropapillary serous carcinomas. American Journal of Surgical Pathology. 2001;25:419–432
  10. Burks RT, Sherman ME, Kurman RJ. Micropapillary serous carcinoma of the ovary: a distinctive low grade carcinoma related to serous borderline tumours. American Journal of Surgical Pathology. 1996;20:1319–1330
  11. Eichorn JH, Bell DA, Young RH, Scully RE. Ovarian serous borderline tumours with micropapillary and cribriform patterns: a study of 40 cases and comparison with 44 cases without these patterns. American Journal of Surgical Pathology. 1999;23:397–409
  12. Scully RE. Histological typing of ovarian tumours. World Health Organization International Classification of Tumours. New York: Springer; 1999;
  13. Rose PG, Rubin RB, Nelson BE. Accuracy of frozen section (intraoperative consultation) diagnosis of ovarian tumours. American Journal of Obstetrics and Gynecology. 1994;171:823–826
  14. Menzin AW, Rubin SC, Noumoff JS, LiVolsi VA. The accuracy of a frozen section diagnosis of borderline ovarian malignancy. Gynecological Oncology. 1995;59:183–185
  15. Hart WR, Norris HJ. Borderline and malignant mucinous tumours of the ovary: histologic criteria and clinical behaviour. Cancer. 1973;31:1031–1045
  16. Siriaunkgul S, Robbins KM, McGowan L, Silverberg SG. Ovarian mucinous tumours of low malignant potential: a clinicopathologic study of 54 tumours of intestinal and Mullerian type. International Journal of Gynecological Pathology. 1995;14:198–208
  17. Riopel MA, Ronnett BM, Kurman RJ. Evaluation of diagnostic criteria and behaviour of ovarian intestinal-type mucinous tumours: atypical proliferative (borderline) tumours and intraepithelial, microinvasive, invasive and metastatic carcinomas. American Journal of Surgical Pathology. 1999;23:617–635
  18. Ronnett BM, Zahn CM, Kurman RJ. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to ‘pseudomyxoma peritonei’. American Journal of Surgical Pathology. 1995;19:1390–1408
  19. Ronnett BM, Kurman RJ, Zahn CM. Pseudomyxoma peritonei in women: a clinicopathologic analysis of 30 cases with emphasis on site of origin, prognosis, and relationship to ovarian mucinous tumours of low malignant potential. Human Pathology. 1995;26:509–524
  20. Prayson R, Hart WR, Petras R. Pseudomyxoma peritonei: a clinicopathologic study of 19 cases with emphasis on site of origin and nature of associated ovarian tumours. American Journal of Surgical Pathology. 1994;18:591–603
  21. Young RH, Gilks CB, Scully RE. Mucinous tumours of the appendix associated with mucinous tumours of the ovary and pseudomyxoma peritonei: a clinicopathological analysis of 22 studies supporting an origin in the appendix. American Journal of Surgical Pathology. 1991;15:415–429
  22. Ronnett BM, Shmookler BM, Diener-West M. Immunohistochemical evidence supporting the appendiceal origin of pseudomyxoma peritonei in women. International Journal of Gynecological Pathology. 1997;16:1–9
  23. Cuatrecasas M, Matias-Guiu X, Prat J. Synchronous mucinous tumours of the appendix and the ovary associated with pseudomyxoma peritonei: a clinicopathologic study of six cases with comparative analysis of c-Ki-ras mutations. American Journal of Surgical Pathology. 1996;20:739–746
  24. Young RH, Hart WR. Metastases from carcinoma of the pancreas simulating primary mucinous tumours of the ovary. American Journal of Surgical Pathology. 1989;13:748–756
  25. Young RH, Scully RE. Ovarian metastases from carcinoma of the gallbladder and extrahepatic bile ducts simulating primary tumours of the ovary: a report of 6 cases. International Journal of Gynecology and Pathology. 1990;9:60–72
  26. Young RH, Scully RE. Mucinous ovarian tumours associated with mucinous adenocarcinoma of the cervix: a clinicopathological analysis of 16 cases. International Journal of Gynecological Pathology. 1988;7:99–111
  27. Hoerl HD, Hart WR. Primary ovarian mucinous cystadenocarcinomas. American Journal of Surgery and Pathology. 1998;22:1449–1462
  28. Nayar R, Siriaunkgul S, Robbins KM. Microinvasion in low malignant potential tumours of the ovary. Human Pathology. 1996;27:521–527
  29. Kempson RL, Hendrickson MR. Ovarian serous borderline tumours: the citadel defended. Human Pathology. 2000;31:525–526 (editorial)
  30. Lee KR, Castrillon DH, Nucci M. Pathologic findings in eight cases of ovarian serous borderline tumours, three with foci of serous carcinoma, that preceded death or morbidity from invasive carcinoma. International Journal of Gynecological Pathology. 2001;20:329–334
  31. Silva EG, Tornos C, Zhuang Z. Tumour recurrence in stage I ovarian serous neoplasms of low malignant potential. International Journal of Gynecological Pathology. 1998;17:1–6

PII: S1521-6934(02)90300-7

doi: 10.1053/beog.2002.0300

Best Practice & Research Clinical Obstetrics & Gynaecology
Volume 16, Issue 4 , Pages 499-512 , August 2002

Article Tools